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Metabolites Produced by Marine and Terrestrial Bacteria Streptomycetes
- In the search for bioactive metabolites from microorganisms, the selection of suitable bacterial strains was carried out based on chemical and biological screening. Fermentation and extraction of the selected strains were done under standard conditions. In the present work, some interesting new compounds isolated from the selected bacterial strains were presented. The new compounds involved the mandalarpyrones, a new isatine derivative, ayeyarwadayquinoline and two new kromycin derivatives. Isolation and structure elucidation of the compounds were performed using various chromatographic methods and their spectroscopic data respectively. On the stage of pure metabolites, antibacterial, antifungal, and cytotoxic activity were measured.
Hnin Yu Win
- Jour. Myan. Acad. Arts & Sc.