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Antibacterial Activity Determination, Phytochemical Screening and Structure Elucidation of Flavonoid Compound Isolated from Indigenous Medicinal Plant (Kyoe-sa-gauk)
- Antibacterial activity of an indigenous medicinal plant Chrozophora plicata (Vahl) A. Juss. Ex Spreng, under family Euphorbiaceae, Myanmar name (Kyoe-sa-gauk), was determined in different solvent extracts with the selected micro-organisms namely Bacilus substilis, Pseudomonous aureus, and Pseudomonous aurigenosa. Ethylacetate and ethanol extracts showed the higher activity than the remaining extracts. Phytochemical constituents of the plants were also examined by phytochemical methods that confirm the presence of alkaloid, glycoside, steroid, and polyphenolic compounds. An unknown compound could be isolated from the plant by column and thin layer chromatographic separation techniques. Its structure could be elucidated by spectral analysis consisting of 1H NMR, 13C NMR, DQF COSY, DEPT, HSQC, PFG HMBC, and EIMS respectively.
Hla Myo Min